![](http://gatewayomega.com/cdn/shop/articles/Untitled-1_2048x.jpg?v=1590158985)
海豹油中富含的DPA是欧米伽3家族重要一员
Gaetan Drouin, Vincent Rioux, Philippe Legrand
Laboratory of Biochemistry and Human Nutrition, Agrocampus Ouest, Rennes, F-35042, France
Abstract
Present in food sources in non-negligible quantities, as well as in human milk, dietary n-3 DPA is of current interest both for its ability to increase EPA and DHA tissue status and for its specific or shared biological effects. Indeed, some evidence showed that dietary n-3 DPA is a source of EPA and slightly DHA in the major metabolic organs. n-3 DPA is also the precursor of a large panel of lipid mediators (protectins, resolvins, maresins, isoprostanes) principally implicated in the pro-resolution of the inflammation with specific effects compared to the other n-3 LCPUFA. Recent results showed that n-3 DPA is implied in the improvement of cardiovascular and metabolic disease risk markers, especially plasma lipid parameters, platelet aggregation, and cellular plasticity. Moreover, n-3 DPA is the most abundant n-3 LCPUFA in the brain after DHA and it could be specifically beneficial for elderly neuroprotection, and early-life development. These results led to the development of two drugs specifically containing n-3 DPA.
Learn more
https://www.sciencedirect.com/science/article/abs/pii/S0300908419300306